Home Print this page Email this page Small font size Default font size Increase font size
Users Online: 739
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Contacts Login 
Year : 2015  |  Volume : 4  |  Issue : 4  |  Page : 212-215

Pediatric hospital admission due to adverse drug reactions: Report from a tertiary center

1 Department of Clinical Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
2 Iranian Adverse Drug Reaction Monitoring Center, Food and Drug Organization, Ministry of Health, Tehran, Iran
3 Department of Clinical Pharmacy; Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran

Correspondence Address:
Toktam Faghihi
Department of Clinical Pharmacy; Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2279-042X.167045

Rights and Permissions

Objective: Adverse drug reactions (ADRs) are known as a cause of hospital admission. We have carried out a prospective study to characterize and assess the frequency, probability, preventability, and severity of ADRs, which lead to hospital admission in children. Methods: In a prospective observational study, a cohort of children admitted to a tertiary pediatric hospital was randomly screened to assess ADR as the cause of admission from June 2014 to January 2015. ADRs causing admissions were detected based on patients' records, interviewing their parents, and confirmation by medical team. The probability of the ADRs was assessed based on WHO criteria and Naranjo tool. The preventability assessment was performed using Schumock and Thornton questionnaire. Findings: Of the 658 evaluated emergency admissions, 27 were caused by an ADR giving an incidence of 4.1%. Among ADRs, 37.1% were estimated to be preventable. Antibiotics were the most common medication class which caused hospital admission. Conclusion: Pediatric pharmacotherapy still needs evidence-based strategies to improve child care including education, monitoring, planning for medications after ADR occurrence, and implementing preventive measures when applicable.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded412    
    Comments [Add]    
    Cited by others 5    

Recommend this journal